About Amoxycillin and Clavulanic acid Combination

Today, Amoxycillion and Clavulanic acid is one of most prescribed antibiotic for various illnesses in India. We can easily find number of brands available in the market for this combination like Augmentin (Glaxo), Moxclav (Ranbaxy), Clavam (Alkam) etc. In recent times, market of this combination has increased many times after the entry of number of cheap brands from the player like Mankind.

Though, worldwide and India, Augmentin holds an undisputed top position in this segment despite priced much higher as compared to other brands. Amoxycillin alone is also a good antibiotic and is one of the most frequently prescribed antibiotics in clinical practice. Amoxycillin is a broad spectrum Aminopenicillin and it belongs to Beta-Lactam group antibiotics. However, wide use of Amoxycillin has caused resistance towards it from various pathogens resulting in the decrease in efficacy of this drug.

To solve this problem, scientists discovered that they can again restore the efficacy of Amoxycillin by combining it with Clavulanic acid. Clavulanic acid itself has very less antibacterial properties, however, due to its suicide inhibitor tendencies for beta-Lactemases (medical name of resistance for Amoxycillin) it clear the way for the action by Amoxycillin against the Bacteria. Though, some pathogens in acute cases have also started showing resistance toward this combination also but still this combination provides a better alternative with Indian doctors to treat their patients.

This combination is widely prescribed in indications like Tonsillitis, Pharyngitis, Sinusitis, Otitis media, Acute or chronic bronchitis, Pneumonia etc. This combination is available in market in tablet, suspension and IV form. In future, also we can hope that this combination will remain the preferred choice antibiotic in India.

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